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Exercise releases factors such as FNDC5, irisin, and IGF-1, which cross the bloodbrain barrier and regulate glioma cells

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Mechanisms of action It has become common to discover a binding of a small molecule to another molecule such as a protein, and assume that this interaction, leading to activation or inhibition of the target, constitutes the mechanism of action of the small molecule at a physiological level

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[DOI] [PubMed] [Google Scholar] 1317.Vanderheyden M, Bartunek J, Knaapen M, Kockx M, De Bruyne B, Goethals M

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