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Description
In addition to its role in glucose homeostasis (T2D), and neuroprotective and antioxidant effects, it also shows anti-inflammatory, anti-fungal, anti-bacterial, and antihypertensive effects [5,100]
Cortisone quiets the pain signal
It shows in Domain-1 the thioredoxin canonical folding, with the three parallel beta-sheets (124) and one antiparallel (3)
3a) and involves negatively charged amino acids on four different helices (1, 2, 5 and 9) of the SemDs rigid core (Fig
