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2.13.1.2 E693del (Osaka) mutation The APP E693-Tg (Osaka) mouse model, which carries the Osaka mutation (APP695) under the control of the mouse prion promoter, expressed comparable levels of mutant human APP and endogenous mouse APP

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For example, foam cells cannot easily escape the intima and are thus trapped due to their diminished migration capacity [9, 10], leading to the accumulation and retention of foam cells in the arterial intima

Although no significant difference was observed, the increase in urinary Na + concentration was delayed, with an increase being observed after 120 min