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In preclinical studies, UPR dysregulation contributes to oxidative damage and hepatocyte death in a mouse model of fructose-induced NAFLD (138)
In contrast, a recent study in Polish women found, instead, a significant decrease of breast cancer risk in individuals with the Leu variant, with an adjusted OR of 0.61 (95%CI, 0.380.97) [152]
Not every pepper is trying to ruin your evening
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