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GGCT is an enzyme involved in the -glutamyl cycle, playing a key role in both the synthesis and degradation of reduced GSH

3,4 There is a dual directional regulation between metabolite levels and inflammatory defenses, 5 and understanding the alterations in the serum metabolome during injuries is critical for making and directing more precise and personalized therapeutic intervention

Clinical translation remains uncertain, as illustrated by the neutral outcome of a trial with an oral p38 inhibitor in non-ST-elevation myocardial infarction [167]

Perelis M, Marcheva B, Ramsey KM, Schipma MJ, Hutchison AL, Taguchi A, et al