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PCD patients can present with symptoms of severe hypoketotic hypoglycaemia, hepatic dysfunction, cardiac arrhythmias, cardiomyopathies or SCD 13,14,15,16,17,18,19

This spike in new cases indicates that narcolepsy risk is strongly increased by DQB1*06:02, young age, and specific immune stimuli (Scammell, 2015)

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Interestingly, patients who received 100 mg CoQ 10 + 500 mg vit E + -blockers, compared to those only treated with -blockers, showed a beneficial effect on inner retinal function, electroretinogram improvement and enhancement of the visual cortical responses (measured by visual-evoked potential enhancement) [91]