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Diagnosis of HAPH often relies on echocardiography, cardiac catheterization, and other methods to assess pulmonary artery pressure and its impact on cardiac function

FOXO4-DRI represents a transformative breakthrough in senescence research that has fundamentally changed our understanding of cellular aging and opened unprecedented opportunities for studying age-related diseases and interventions

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Hence, our data suggests that only a very short pre-treatment of erastin suffices to synergize with cisplatin to efficiently induce cancer cell death, findings that might guide us in the design of novel cancer treatment paradigms.