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Description

Renal OCTN2 expression and activity increase when the carnitine concentration is reduced in the plasma and/or glomerular filtrate, whereas OCTN2 mRNA expression levels remain unchanged in the gut, liver, or skeletal muscle [254], highlighting the central role of the kidney in maintaining carnitine homeostasis

Regular use at the same time each day yields better results than irregular consumption

Lancet Neurol 11:521534 Abbott CA, Malik RA, van Ross E, Kulkarni J, Boulton A (2011) Prevalence and characteristics of painful diabetic neuropathy in a large community-based diabetic population in the UK