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NRF2 in Amyotrophic Lateral Sclerosis ALS is the most common motor neuron disease in adults and estimates have reported that 31,000 patients live with ALS in the US, where on average 5,000 new patients are diagnosed annually (Mehta et al., 2023)

The slides were then incubated with Alexa Fluor 488-conjugated goat anti-mouse IgG (diluted 1:600, Invitrogen) for 1 h at 37C

Major advances in the management of relapsed/refractory multiple myeloma include BCMA-targeting treatments such as the CAR-T therapies ciltacabtagene autoleucel and idecabtagene vicleucel, and the bispecific antibodies teclistamab, elranatamab, and linvoseltamab

It is also known to reduce spasticity-related post-SCI pain