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AAOS Board meeting, Zoom Lecture

Strikingly, the study revealed that the immune cells of these patients act as an "energy sink." In a desperate attempt to survive the overwhelming oxidative stress, the immune cells upregulate their own intracellular glutathione production
Telikepalli, S
Indeed, the European multicenter study coordinated by Graham reports that, whereas basal hyperhomocysteinemia only shows an additive effect with hypercholesterolemia, it has a synergistic effect with both hypertension and smoking on the incidence of atherosclerotic vascular disease (Graham et al, 1997)
