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Studies in human hepatoma cells have shown that GSTP1 is able to bind to signal transduction and transcriptional activator 3 (STAT3) to form the GSTP1-STAT3 complex, inhibiting epidermal growth factor (EGF)-mediated phosphorylation of STAT3 tyrosine and preventing its transcriptional activity, thereby reducing cell proliferation and halting the cell cycle [73]

Bone marrow mesenchymal stem cells combined with ultra-purified alginate gel as a regenerative therapeutic strategy after discectomy for degenerated intervertebral discs

Li H, Yang P, Wang J, Zhang J, Ma Q, Jiang Y, et al