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NOX: NADPH oxidase NQO1: NADPH:quinone oxidoreductase 1 SVCT: Sodium-dependent vitamin C transporter Tet: Ten eleven translocase References Szent-Gyorgyi A (1928) Observations on the function of peroxidase systems and the chemistry of the adrenal cortex: description of a new carbohydrate derivative

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Initiation and progression of PD is dependent upon cellular events, including failures in the protein degradation machinery, oxidative stress, mitochondrial dysfunction, defects in mitochondrial autophagy (mitophagy) and the continuous accumulation of -synuclein, driven through cell to cell interactions between glial cells and neurons that ultimately lead to apoptosis [7,10,18]

1 Due to numerous drug interactions resulting in either potentiation of the warfarin effecthence increased risk of bleedingor its decreased effect, concomitant use with many medications commonly prescribed in dentistry should be avoided