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464,465 Ionizing radiation can alter the levels of RNA modifications and the activity of related enzymes, which in turn may modulate the sensitivity of cancer cells to radiation

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The role of cellular protection in response to ROS accumulation has been reported, and the signal of preconditioning that leads to this protection was related to Hormesis, which means a dose-response relationship of ROS, at low levels, generates a stimulus of neurodegenerative diseases, while its accumulation (high concentration) generates an inhibition of the effect through preconditioning [21-23]

Exosomes in the hypoxic TME: from release, uptake and biofunctions to clinical applications