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RTqPCR mRNA measurement In rats with strokereperfusion at 1 and 24 hr, the beneficial effect of BPC 157 therapy during reperfusion was associated with strongly elevated ( Egr1, Akt1, Kras, Src, Foxo, Srf, Vegfr2, Nos1, and Nos3 ) and decreased ( Nos2 and Nfkb1 ) gene expression, while Mapk1 remained unchanged throughout both time intervals (Figure 6)

Deng T, Chen D, Chen F, Xu C, Zhang Q, Li M, Wang Y, He Z, Li M, He Q

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Chromatographic purification of a bioactive component of urine/bladder tissue followed by mass spectrometry revealed a glycosylated nonapeptide (APF peptide), which appears to be a fragment of the frizzled-8 (FZD8) G protein-coupled receptor 27