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Rifampicin has shown effectiveness in alleviating cholestatic pruritus but poses a hepatotoxicity risk in up to 13% of patients with prolonged use and has not been studied for pruritus in cirrhosis (4, 23)

Bacteroides and Bifidobacterium increase the production of secondary bile acids in the gut, impacting host metabolism in several crucial ways and playing an essential role in regulating lipid and glucose metabolism and energy balance

Gevi, F., Zolla, L., Gabriele, S

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