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GENVOYA is not recommended in patients with severe renal impairment (estimated creatinine clearance of 15 to below 30 mL per minute), or in patients with ESRD who are not receiving chronic hemodialysis, as the safety of GENVOYA has not been established in these populations [see Dosage and Administration (2.3), Warnings and Precautions (5.4) and Clinical Pharmacology (12.3)]
A second group of self-selected healthy volunteers on the Procter & Gamble campus (all omnivores) gave consent and donated fecal samples for microbial culture and biochemical analyses

These compounds are essential for maintaining gut health and have been shown to have several beneficial effects on the body, including reducing inflammation, improving insulin sensitivity, regulation of gene expression, and regulating the immune system (62, 65)
