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The activity of IELs and LP T cells is kept in check by regulatory T cells (Tregs) to prevent excessive inflammation at mucosal surfaces (Harrison and Powrie, 2013
Glutamate triggers long-distance, calcium-based plant defense signaling
35 IshikawaY.TachibanaM.MatsuiC.ObataR.UmezawaK.NishiyamaS
Increased ECM stiffness engages innate immunity (e.g., tenascin C-CD47 phagocytic signaling in macrophages), underscoring immune regulation in the TME [42]
