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For areas with substantial fat like the abdomen in most adults, insert at 90 degrees straight down
Reported biochemical potency against human NNMT is in the low-micromolar range with cellular EC values in the low-micromolar range for suppression of 1-MNA and lipogenesis, with selectivity over related methyltransferases and NAD-salvage enzymes [1,6,7]
Understanding these effects is crucial for responsible research use and appropriate safety monitoring
