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In the ischemia/reperfusion-induced fibrosis C57BL/6J mouse model, transcriptomic and metabolomic analyses showed that dapagliflozin treatment mitigated accumulation of tricarboxylic acid (TCA) circulating metabolites and up-regulation of inflammation in fibrotic renal cortical tissue

[DOI] [PubMed] [Google Scholar] 88.Hirst WD, Abrahamsen B, Blaney FE, et al

The principle is straightforward: combine peptides that complement each other across different mechanisms rather than stacking multiple peptides that do the same thing at higher intensity

[DOI] [PubMed] [Google Scholar] 69.Kandola A, Ashdown-Franks G, Hendrikse J, Sabiston CM, Stubbs B