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Polyphenols antitumor properties may be attributed to its suppression of cell division and activation of phase II antioxidant enzymes, such as superoxide dismutase, glutathione-S-transferase, and glutathione peroxidase and reductase [416]

Conversely, in a pressure overload HF model, overexpression of BDH1 can alleviate cardiac remodeling and DNA damage (Uchihashi et al., 2017)

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