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(1997) Phosphoinositide-specific phospholipase C 1 activity toward micellar substrates, inositol 1,2-cyclic phosphate, and other water-soluble substrates: a sequential mechanism and allosteric activation

Abbreviations PCOS: Polycystic ovary syndrome AI: Artificial intelligence ML: Machine learning DL: Deep learning SVM: Support vector machine AUC: Area under the curve PCOM: Polycystic ovary morphology MRI: Magnetic resonance imaging CNN: Convolutional neural network RF: Random forest NCBI: National Center for Biotechnology Information GEO: Gene expression omnibus m6A: N6-methyladenosine ANN: Artificial neural network GLM: Generalized linear model Acc: Accuracy RBF: Radial basis function GMM: Gaussian mixed model KNN: K-nearest neighbor Y/N: Yes or no LASSO: Least absolute shrinkage and selection operator TOPSIS: Technique for order of preference by similarity to ideal solution References Abbott D, Dumesic DJC (2021) Passing on PCOS: new insights into its epigenetic transmission

2, panel c)

When it does occur in families, it does so in an autosomal-dominant fashion, meaning that half of the family is at risk, she adds