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Increasing mitochondrial pyruvate inhibits the PDKs allowing for rapid decarboxylation of pyruvate by the PDHc ensuring continued entry of glucose into the glycolytic stream

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Genes encoding proteins implicated in lipid transport ( VPS13D / vps13d ) and organelle regulation ( RAB7 / rab-7 ) are probably involved between these two organelles (because their deficiency uncouples co-regulation of lipid droplet and peroxisome number)