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Other risk factors, including heavy metals, such as mercury and lead, are not cleared quickly if the individual has become low in sulfur-containing compounds

Although Carboxylesterase (CCEs) have been mostly associated to organophosphate resistance in mosquitoes, their role in pyrethroid resistance is probable

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Once there exists an accumulation of DAMPs, it would trigger the amplification of tissue inflammation, leading to more severe inflammation and CD, forming a vicious circle and disrupting the normal physiological function of tissues and organs (Linkermann et al., 2014