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dysglycaemia (prediabetes or type 2 diabetes mellitus), hypertension, dyslipidaemia, obstructive sleep apnoea or cardiovascular disease

doi: 10.3390/ijms22126521

Behavioral interventions alone rarely achieve more than 5-10% sustained weight loss, while tirzepatide consistently produces 15-23% reduction in clinical trials

Currais A, Prior M, Dargusch R, Armando A, Ehren J, Schubert D, Quehenberger O, Maher P (2014) Modulation of p25 and inflammatory pathways by fisetin maintains cognitive function in Alzheimers disease transgenic mice
