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Description
While the canonical IL-4/STAT6 pathway is the well-established initiator of the M2 transcriptional program, our findings suggest that direct activation of PKA in M1 macrophages (using Db-cAMP) was sufficient to significantly enhance efferocytosis
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Notably, the body stores some vitamin B12 in the liver, which can last for years
The skin is pinched to lift the subcutaneous tissue away from the muscle, and the injection is administered slowly to minimize discomfort
