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de Rey Pailhade, in 1888, first identified the molecule from yeast extracts
doi:10.1038/nrneurol.2013.132 pmid:23857047 Tsuda M (2017) P2 receptors, microglial cytokines and chemokines, and neuropathic pain
P2RX7 protein can be expressed but persists in the cytoplasm in an inactivated form (Benzaquen et al., 2019)
