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10.1038/s41562-023-01706-6 10.1038/s41562-023-01706-6 [DOI] [PMC free article] [PubMed] [Google Scholar] Kontush K, Schekatolina S (2004) Vitamin E in neurodegenerative disorders: Alzheimers disease

There are some methods like reducing exposure to cold, calcium and magnesium salts, amifostine could be beneficial in acute OIPN prevention and dose modification, changing in schedule glutathione, duloxetine, selective serotonin reuptake inhibitors, carbonic anhydrase inhibitor in chronic OIPN prevention

Furthermore, the protein disulfide isomerase (PDI) directly interacts with integrins, mediating disulfide-thiol exchange, resulting in conformational changes and activation (Popierlarski et al

However, because it is an autoimmune disease, extra treatments may be necessary, too, such as corticosteroids or immunosuppressants in serious instances, to handle inflammation and autoimmunity