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Many researchers have used high-throughput sequencing to explore the correlation between genetic susceptibility factors for IBD and gut microbiota, further elucidating their connection [128, 129]

Studies show that sublingual (under the tongue) and nasal forms of B12 supplements offer a similar absorption rate as injections (Temova Rakua et al., 2022)

[] d = -46.0 (c = 0.25, CHCl 3 ), Rf = 0.19 (hexane/acetone 65/35), 1 H NMR (400 MHz, CDCl 3 ) (ppm) 7.417.15 (m, 15 H, arom.), 7.02 (d, J = 7.5 Hz, 1 H, H-6), 5.09 (d, J = 2.7 Hz, 1 H, H-1), 5.05 (d, J = 7.5 Hz, 1 H, H-5), 4.38 (s, 0.5 H), 4.27 (d, J = 2.2 Hz, 1 H), 3.88 (d, J = 12.2 Hz, 1 H), 3.75 (d, J = 10.6 Hz, 1 H), 1.52, 1.33 (2 x s, 2 3 H, 2 x i -propylidene C H 3 )

Yousef, A, Yousef, M, Zeineddine, MA, More, A, Fanaeian, M, Chowdhury, S, Knafl, M, Edelkamp, P, Ito, I, Gu, Y, Pattalachinti, V, Naini, ZA, Zeineddine, F, Peterson, J, Alfaro, KD, Foo, WC, Jin, J, Bhutiani, N, Higbie, V, Scally, CP, Kee, BK, Kopetz, S , Goldstein, D, Strach, M, Williamson, A, Aziz, O, Barriuso, J, Uppal, A, White, MG, Helmink, BA, Fournier, KF, Raghav, KS, Taggart, MW, Overman, MJ, Shen, JY
