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Human data is still very limited, including small pilot work such as the knee pain survey of 16 patients, plus a few other early studies and reviews calling out the lack of large, rigorous trials

J Biochem Mol Toxicol 27:451456

It showed that both effectively improve serum vitamin B12 levels for people suffering from vitamin B12 deficiency

When you take oral B12 supplements, they must pass through the stomach and intestines, where absorption can be limited by factors like stomach acid and the presence of a protein called "intrinsic factor." An injection circumvents these potential barriers, ensuring maximum absorption and making the vitamin immediately available to your body