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See the 2026 updates section of this guide for the complete breakdown with source citations

Se deficiency negatively impacts immune cells during activation, differentiation, and proliferation through redox signaling, oxidative burst, calcium flux, and the subsequent effector functions of immune cells (Huang et al., 2012

The first line of antioxidant defense against ROS is very efficient and is predominantly represented by the intracellular antioxidant pool, consisting of antioxidant enzymes, including Cu,Zn-SOD (SOD1), catalase, glutathione peroxidase (GPX), peroxiredoxins (PRDx)

Eating green foods, including asparagus, avocado, cucumber, green beans, and spinach raw or slightly steamed, is preferable to preserve both forms of glutathione (GSH and GSSG)