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Mammalian GPX4 contains a selenocysteine in its catalytic site crucial for reactions to occur and it thus a selenoprotein

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Therefore our list is a bit longer, and we have preferred to classify the effect into two groups, where predictable haemolysis means that AHA can be expected in a G6PD-deficient patient, whereas possible haemolysis means that AHA may or may not take place, depending on dosage, other concomitant drugs, co-morbidity and other factors

Biochim Biophys Acta (BBA)-Reviews Cancer (2009) 1796(2):16275
