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For example, research indicates that low glutathione levels are associated with chronic diseases such as diabetes and heart disease

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Subsequent studies revealed that ArfGAP1 gene silencing rescues the inhibition of neurite outgrowth induced by G2019S LRRK2 in rodent primary cortical neurons, whereas co-expression of wild-type LRRK2 and ArfGAP1 synergistically promotes neurite outgrowth deficits (Stafa et al., 2012

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