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Folate-rich diet increased DNA methylation of genes such as p16 [114] in mouse colon and protooncogenes such as PDGF-B (platelet-derived growth factor-B), Ras (rat sarcoma), and survivin in a mouse model of gliomagenesis [115]

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Orthopedics 28(6):573-7

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Previous studies have shown that, under certain circumstances, such as the induction of ER stress or blockade of ER-to-Golgi transport, the ER core-glycosylated form of CFTR, including the F508 mutant, can be transported to the cell membrane via the UPS pathway, bypassing the Golgi apparatus 12,13,14,15

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