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[DOI] [Google Scholar] Yin H
Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway
In a white opaque flat-bottom 96-well microtiter plate, 25 L of parasite samples from each condition were seeded in triplicate
They demonstrated that melatonin (3 mg/kg, administered intravenously at 3, 6, and 12 h post-cecal ligation and puncture) significantly improved survival, stabilized blood pressure, restored vascular responsiveness to norepinephrine, and reduced organ injury markers
