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Description
Tulpule and Dringen, 2013)
NF1 has an unusually high mutation rate, estimated at 2.4 105 to 10 105 gametes per generation, one of the highest of known inherited disorders.2 This may reflect the large size of the gene, which spans 350 kb of genomic DNA, and contains 59 exons which encode a peptide containing over 2,800 amino acids
Nrf2-dependent glutamate-L-cysteine ligase catalytic subunit expression mediates insulin protection against hyperglycemia-induced brain endothelial cell apoptosis
[DOI] [PubMed] [Google Scholar] 105.Shin S., Stewart R., Ferri C.P., Kim J.M., Shin I.S., Kim S.W., Yang S.J., Yoon J.S
