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Description
The injection takes only seconds with a very fine needle, usually causing little to no discomfort

Implications Resistance mechanisms that undermine the immunomodulatory effects of CD38targeting therapies can be tumor intrinsic, such as the downregulation of CD38 surface expression and expression of complement inhibitor proteins, and immune microenvironmentrelated, such as changes to the natural killer (NK) cell numbers and function in the bone marrow niche
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They can explain the process for obtaining coverage and any additional requirements
