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Nat Rev Drug Discov 22:185212 Lpez-Pingarrn L, Almeida H, Soria-Aznar M et al (2023) Role of oxidative stress on the etiology and pathophysiology of amyotrophic lateral sclerosis (ALS) and its relation with the enteric nervous system

To see how, we begin with the concept of entropy

A more recent study found that following cytarabine chemotherapy, the enriched-senescent AML cells produced a senescence-associated secretory phenotype (SASP) by increasing NF-B transcription through the ataxia telangiectasia and Rad3-related (ATR) activities, and regained stemness properties sufficient to restore leukemia (129)

doi: 10.1016/j.cca.2015.07.009 121