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2019) analyzed the ASD diagnosis of 2,961 children from 38,331 pregnant individuals exposed to agricultural pesticides and found an increased risk associated with pesticide exposure, including chlorpyrifos (Odds Ratio [OR] 1.15, 95% CI: 1.20, 1.29), diazinon (OR 1.14, 95% CI: 1.03, 1.26) and avermectin (OR 1.14, 95% CI: 1.03, 1.26) (von Ehrenstein et al

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Oral mucosal melanin hyperpigmentation may be secondary to disease, medications, or smoking, and physiological oral melanin hyperpigmentation may be clinically and histopathologically similar so that the differentiation between pathological and physiological oral melanosis can at times be difficult