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Description
DHODH tangoing with GPX4 on the ferroptotic stage
These hydroperoxides degrade into reactive aldehydes such as MDA and 4-HNE, which covalently bind to proteins and DNA, disrupting cellular functions (Figure 3) [157,158,159]
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Apoptosis in arsenic trioxide-treated Calu-6 lung cells is correlated with the depletion of GSH levels rather than the changes of ROS levels
