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By reducing NNMT activity, 5-Amino-1MQ is thought to raise cellular levels of NAD, enhance metabolic rate, promote lipolysis (fat breakdown), shrink white adipose tissue, and even promote a browning or beiging of fat (i.e
Through interaction with and suppression of PGAM5 and phosphorylation of Ser13 in FUNDC1, the essential anti-apoptotic protein BCL-xL negatively regulates FUNDC1-mediated mitophagy [109]
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