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Although existing studies have elucidated the genetic basis of IMF deposition in chickens from the perspectives of interspecific and intraspecific differences, several limitations remain: 1) Current genetic mechanism studies have predominantly focused on specific genes or pathways (e.g., FABP4 and PPAR), yet they lack systematic integration of multidimensional regulatory networks (e.g., the interactions among SNPs, epigenetic modifications, and noncoding RNAs (ncRNAs))

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Extracellular matrix interactions provide tumor cells with an escape mechanism for commitment to differentiation

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