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In posterior segments of the gut (e.g., the cecum and proximal large intestine), gut microbes directly cleave the CN bond of carnitine to release TMA, which subsequently enters the liver through the portal circulation, is converted to TMAO by hepatic flavin monooxygenases (FMOs) [242, 243], and eventually enters the blood circulation [244]

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In realt, la ossidazione degli acidi grassi un'altra via per la degradazione degli acidi grassi tipica di alcune specie di vertebrati e mammiferi, che si verifica nel reticolo endoplasmatico del fegato e dei reni

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