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low glutathione levels are low cellular pyridoxal 5ʹ-phosphate decrease neurotransmitter and concentrations and increase susceptibility to hydrogen peroxide toxicity in SH-SY5Y cells How to Identify the 4
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Hambach J, Fumey W, Sthler T, Gebhardt AJ, Adam G, Weisel K, et al

Leveraging comprehensive data from 13,091 blood donors in the REDS RBC-Omics study, we identified caffeine as a significant modulator of red blood cell (RBC) storage quality and transfusion outcomes

The inverse association between changes in Chac1 mRNA expression level and glutathione level suggests a role of CHAC1 in glutathione depletion in skeletal muscle

PLoS ONE 9 , e111838 (2014)
