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This equation replaced the fixed triglyceride divisor in the Friedewald formula with a variable factor that depends on both triglyceride and non-high-density lipoprotein-cholesterol (non-HDL-C) levels

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The concentration remains fixed once water is added dose adjustment happens through volumetric measurement, not reconstitution changes

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FadR is the key regulator

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78 Moreover, glucose-6-phosphate dehydrogenase (G6PD), a pivotal enzyme in the PPP, also serves as a significant substrate for lactylation

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