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doi: 10.1056/NEJMoa1103690

Meanwhile, HIF-1 can inhibit chondrocyte catabolism and maintain the dynamic balance of articular cartilage matrix by regulating NF-B signalling and limiting the expression of matrix metalloproteinase (MMP)-13 (58)

Biosensor fluorescence ratios were calculated for Peredox and NAPstar family as TS/mCherry and for the roGFP2 family as 400/482 nm