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Side Effects Gastrointestinal symptoms: Most common adverse effects were mild-to-moderate nausea, vomiting, and diarrhea, occurring primarily during dose escalation [6] [12]
doi: 10.1677/joe.0.1810039
The mean time between baseline testing and follow-up was 5 months (range = 48 months)
The Diabetes Prevention Program Outcomes Study (DDPOS) showed that combined low and borderline-low vitamin B 12 levels were more common in metformin users after 5 and 13 years of use, compared with levels in non-users
