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2 Pathogenesis of pulmonary fibrosis Tissue repair following injury is an inherent biological mechanism that restores tissue integrity through the organized replacement of damaged or deceased cells (Figure 1: the initial sustained injury phase, the inflammatory cell migration phase, the fibroblast migration/proliferation/activation phase and finally, the excessive deposition of ECM and fibrosis phase
The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides

In pancreatic cancer cells, the inhibition of autophagy leads to cell growth inhibition [131]

n = 8) groups
