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In symptomatic cases, history-taking and a physical exam are essential to making an accurate diagnosis

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TnC has a multidomain structure consisting of a coiled-coil region followed by multiple EGF-like domains, fibronectin type-III (FN III) domains, and a fibrinogen C-terminal domain (Okada and Suzuki, 2020)

Clinical case In order to show that D-dimer testing is often misused (which can lead to inappropriate diagnosis and therapies), we present here a typical case involving a 76-year old woman referred to us three years after an unprovoked deep vein thrombosis (DVT) of the popliteal vein of the left leg