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430 SGM older adults also have lower rates of health care access and preventive health screenings, in part due to experiencing barriers such as discrimination and heterosexist attitudes in health care settings

Downstream effects via the active metabolite Pro-Gly-Pro, BDNF and NGF mRNA upregulation, and enkephalinase inhibition persist for 12 to 24 hours, which is why dosing frequency is set by downstream windows rather than plasma kinetics

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