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Nutrient experts such as Dr Bodo Kuklinski therefore recommend taking biotin as part of a vitamin B12 therapy: Vitamin B12 has no effect without an accompanying biotin intake [] Under vitamin B12 therapy, the need for biotin increases, and if not supplemented, skin problems, brittle hair and nails as well as spots occur

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This is difficult to determine in the laboratory, because unfortunately there is no simple test for a biotin deficiency

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